Dimethyltryptamine (DMT) is a hallucinogenic drug in the tryptamine family that occurs naturally in many plants and animals. Many refer to it as the spirit molecule. The compound produces a brief but intense visual and auditory hallucinogenic experience.
DMT naturally comes from plants, and is also naturally produced in the human body. It is a Schedule I controlled substance, supposedly having a high potential for abuse and no recognized medical use. However, DMT is used in some religious and spiritual ceremonies around the globe, usually from Ayahuasca, which lasts significantly longer than a normal, 5-15 minute DMT trip. DMT has been used for thousands of years, being consumed orally, or smoked in a pipe. It interacts with the serotonin receptors in your brain to produce visual and auditory hallucinations, euphoria, and an altered sense of space, body, and time. Many users describe profound, life-changing experiences such as visiting other worlds, talking with alien entities known as “DMT elves” or “machine elves,” and total shifts in the perception of identity and reality. DMT is considered to have the lowest side effect profile compared to other psychedelic drugs. Anecdotal evidence suggests DMT does not cause physical dependence or addiction, but users may develop psychological cravings for the drug. Frequent use of DMT use does not seem to induce tolerance of the drug.
A 30 to 150 mg smoked dose can be felt almost instantly and the peak of the experience lasts between 3 to 5 minutes. It can be up to 30 to 45 minutes until a user feels completely normal again.
DMT should not be used by people who take antidepressants or have family history of mental-illness or schizophrenia. Because it is structurally related to the neurotransmitter serotonin and, in rare cases, a condition called serotonin syndrome is a potentially lethal health risk associated with its use. Serotonin syndrome occurs when the body accumulates an excessive amount of serotonin. The condition is often caused by taking a combination of different drugs.
The compound is being tested privately as a potential solution to drug addiction and PTSD.